Licoflavonol
R3 577,89
IUPAC Name: 3,5,7-Trihydroxy-2-(4-methoxy-phenyl)-6-(3-methyl-but-2-enyl)-chromen-4-one
Synonyms: –
CAS Number: 60197-60-6
PubChem SID: xxxx
Molecular Formula: C20H18O6
Molecular Weight: 354.35 g/mol
Purity: ≥98%
Pack Size: 1 mg
Description
Licoflavonol is a prenylated flavonoid compound isolated from licorice (Glycyrrhiza species) .
Licoflavonol reduces uric acid levels in renal tubular epithelial cells and improves oxidative stress damage induced by high uric acid. It increases the activity of antioxidant enzymes (SOD, CAT) and glutathione (GSH), while decreasing malondialdehyde (MDA) and hydrogen peroxide (H2O2). Licoflavonol strongly inhibits the secretion of Salmonella pathogenicity island 1 (SPI-1)-associated effector proteins. It does not affect bacterial growth or flagellar protein secretion, making it a promising candidate for anti-virulence drugs targeting Salmonella infections.
