2α,3β-Oleanan-12-ene-diol
R3 100,00
IUPAC Name: 4,4,6a,6b,8a,11,11,14b-Octamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydro-picene-2,3-diol
Synonyms: –
CAS Number: –
PubChem SID: xxxx
Molecular Formula: C21H32O3
Molecular Weight: 422.52 g/mol
Purity: ≥98%
Pack Size: 1 mg
Description
2α,3β-Oleanan-12-ene-diol is a pentacyclic triterpenoid with hydroxyl groups at the 2α and 3β positions on the oleanan-12-ene skeleton. This compound has been isolated from the sap and stem bark of Staudtia kamerunensis Warb. (Myristicaceae) and Terminalia arjuna. It is also reported as a major component in the sap of Staudtia kamerunensis.
It demonstrated significant antibacterial properties, particularly against Gram-negative bacterial strains. The lowest MIC value reported was 15.625 μg/mL, and its activity was doubled against Gram-negative bacteria compared to other isolates. It also exhibited cytotoxic effects against human prostate cancer cell lines (DU145, PC3, LNCaP) with CC50 values ranging from 18–22 μg/mL, and a selectivity index greater than 2, indicating potential for selective cytotoxicity.
