Oleanolic Acid
R500,00
IUPAC Name: (4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-10-hydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid
Synonyms: Oleanic acid, Caryophyllin, Astrantiagenin C
CAS Number: 508-02-1
PubChem CID: 10494
Molecular Formula: C₃₀H₄₈O₃
Molecular Weight: 456.7 g/mol
Purity: ≥98%
Pack Size: 50 mg
Available on backorder
Description
Oleanolic acid is a naturally occurring pentacyclic triterpenoid widely distributed across the plant kingdom, notably in species such as Salvia miltiorrhiza, Sambucus chinensis, Olea europaea, and Ligustrum lucidum. Functioning as a fundamental plant-derived bioactive, Oleanolic acid serves as an aglycone backbone for numerous triterpenoid saponins, contributing significantly to plant defense mechanisms and bioactivity.
In biomedical research, Oleanolic acid has garnered substantial attention due to its anti-inflammatory, hepatoprotective, and antioxidant properties, demonstrated in both preclinical and clinical models. Its mechanisms of action include the modulation of nuclear factor-kappa B (NF-κB), activation of the Nrf2 antioxidant response pathway, and inhibition of oxidative stress-related enzymes. These bioactivities make it a leading candidate in the development of natural therapeutics targeting liver diseases, metabolic syndrome, cancer, and inflammatory conditions.
Due to its structural versatility and therapeutic relevance, Oleanolic acid continues to be a central molecule in phytochemical investigations, structure–activity relationship (SAR) studies, and drug development pipelines focusing on natural product scaffolds. Its widespread occurrence and established safety profile also support its inclusion in nutraceuticals, cosmeceuticals, and functional food formulations.
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